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POLH antibody [5H10]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX00871

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

POLH antibody [5H10]

别名:

DNA polymerase eta , POLH , RAD30 , RAD30A , XPV

反应种属:

Human

宿主来源:

Mouse

实验应用:

ICC/IF, WB

同种型:

IgG1

免疫原:

Human recombinant full-size Pol eta tagged with His6

克隆性:

Monoclonal

克隆号:

5H10

纯化方式:

Purified by salting-out and ion-exchange chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

Filter-sterilized PBS, 50% Glycerol, no preservatives.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

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