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折扣/货期| 货号：GTX53769 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PPM1F antibody [AT6D11]
别名:
protein phosphatase, Mg2+/Mn2+ dependent 1F , CAMKP , CaMKPase , FEM-2 , POPX2 , hFEM-2
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, WB
同种型:
IgG1
免疫原:
Recombinant human PPM1F (1-454aa) purified from E. coli
克隆性:
Monoclonal
克隆号:
AT6D11
纯化方式:
By protein-A affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
50
产品形式:
Liquid
存储溶液:
PBS, 10% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. [provided by RefSeq, Jul 2008]
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