| 货号:GTX83275 | 规格:100μl | 目录价:¥5600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PRAK antibody [7H10B4]
别名:
mitogen-activated protein kinase-activated protein kinase 5 , MAPKAP-K5 , MK-5 , MK5 , PRAK
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IHC-P, WB
同种型:
IgG1
免疫原:
Purified recombinant fragment of PRAK expressed in E. Coli.
克隆性:
Monoclonal
克隆号:
7H10B4
纯化方式:
Unpurified
偶联:
Unconjugated
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Ascites, 0.03% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
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