官网链接
折扣/货期| 货号：GTX23422 | 规格：100μl | 目录价：￥5300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PREB antibody
别名:
prolactin regulatory element binding , C85705
反应种属:
Mouse
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
Recombinant mouse PREB.
克隆性:
Polyclonal
克隆号:
纯化方式:
Ammonium sulfate precipitation
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
45
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Prolactin (PRL) expression in the pituitary is limited to specific cells. Pit-1 is a pituitary specific transcription factor that plays an important role in PRL expression, both in mature organism and during development. The PRL promoter contains numerous Pit-1 binding sites and these sites have been implicated in both basal level and kinase-mediated gene expression. The most proximal of these binding sites, termed 1P, has been shown to direct a response to numerous signals, such as cAMP and various G-proteins. A novel protein, termed PREB (prolactin regulatory element binding protein), has been recently identified that regulates PRL gene expression through the 1P site, though it contains no discernable DNA-binding motif. Recent studies suggest that PREB is encoded by a single-copy gene in both mice and humans and exhibits nuclear accumulation in pituitary cells. Evidence suggests that PREB is a novel transcription factor that assists in PRL expression whether alone, or in concert with Pit-1.
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询