官网链接
折扣/货期| 货号：GTX116051 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX116051-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Progesterone Receptor antibody [N1], N-term
别名:
progesterone receptor , NR3C3 , PR
产品描述:
The progesterone receptor (PR) is a well-known estrogen receptor (ER) target gene that is expressed in over two-thirds of ER-positive breast cancers. PR protein has a predicted molecular weight of 99kDa. It acts as a transcriptional regulator and activator of signal transduction pathways (i.e., MAPK, PI3K/Akt, and c-Src) that can drive proliferative signaling in breast cancer cells.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-P
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Progesterone Receptor. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.33 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 10% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined. [provided by RefSeq]
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