| 货号:GTX133091 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX133091-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
PSD95 antibody
别名:
discs large MAGUK scaffold protein 4 , Dlgh4 , PSD-95 , PSD95 , SAP90 , SAP90A
产品描述:
PSD95 antibody recognizes postsynaptic density protein 95, an ~80 kDa multidomain scaffold protein enriched at neuron postsynaptic excitatory membranes. It belongs to the membrane-associated guanylate kinase (MAGUK) family, which also contains PSD-93, SAP97 and SAP102. PSD95 is one of the most abundant proteins in the PSD, and functions in synapse maturation, strength, and plasticity.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ICC/IF, IHC-Fr, IHC-P, WB
同种型:
IgG
免疫原:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of mouse PSD95. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
1.31 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
80
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ACCN3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B.
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