PTPN12 antibody [N1N2], N-term-多抗-深圳欣博盛生物科技有限公司

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PTPN12 antibody [N1N2], N-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX102542	规格：100μl	目录价：￥4000
货号：GTX102542-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PTPN12 antibody [N1N2], N-term

别名:

protein tyrosine phosphatase non-receptor type 12 , PTP-PEST , PTPG1

反应种属:

Human, Rat

宿主来源:

Rabbit

实验应用:

ICC/IF, IHC-P, WB

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the N-terminus region of human PTPN12. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.93 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains a C-terminal PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life. This PTP was found to bind and dephosphorylate the product of the oncogene c-ABL and thus may play a role in oncogenesis. This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin. This suggests it has a regulatory role in controlling cell shape and mobility. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

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