PTPRB antibody, Internal-多抗-深圳欣博盛生物科技有限公司

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PTPRB antibody, Internal

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX88020

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PTPRB antibody, Internal

别名:

protein tyrosine phosphatase receptor type B , HPTP-BETA , HPTPB , PTPB , R-PTP-BETA , VEPTP

反应种属:

Human

宿主来源:

Goat

实验应用:

FCM, ICC/IF

靶标/特异性:

This antibody is expected to recognize both reported isoforms (NP_001103224.1; NP_002828.3).

同种型:

IgG

免疫原:

Peptide with sequence C-ENHSFSQERTVPDK, from the internal region of the protein sequence according to NP_001103224.1; NP_002828.3.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

偶联:

Unconjugated

产品浓度:

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

TBS, 0.5% BSA, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

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