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折扣/货期| 货号：GTX83761 | 规格：100μl | 目录价：￥7300 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PTPRE antibody [2A9]
别名:
protein tyrosine phosphatase receptor type E , HPTPE , PTPE , R-PTP-EPSILON
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, IHC-P, WB
同种型:
IgG2b
免疫原:
Full length human recombinant protein of human PTPRE (NP_006495) produced in HEK293T cell.
克隆性:
Monoclonal
克隆号:
2A9
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.79 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
81
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function. Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake. Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+).
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