PVR Recombinant Protein-其他重组蛋白-深圳欣博盛生物科技有限公司

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PVR Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：96-116

规格：0.1 mg

目录价：￥8687.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

PVR Recombinant Protein

别名:

PVR, FLJ25946, PVS, CD155, TAGE4, HVED, NECL5

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

CD155 is a Type I transmembrane glycoprotein in the immunoglobulin superfamily. Commonly known as Poliovirus Receptor (PVR) due to its involvement in the cellular poliovirus infection in primates, CD155's normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155/PVR was originally isolated based on its ability to mediate polio virus attachment to host cells. The fulllength (or CD155 alpha isoform) is synthesized as a 417 amino acid (aa) precursor that contains a 20 aa signal sequence, a 323 aa extracellular region, a 24 aa TM segment and a 50 aa cytoplasmic tail. The extracellular region contains one N terminal V type and two C2 type Ig like domains. CD155 is a transmembrane protein with 3 extracellular immunoglobulin-like domains, D1-D3, where D1 is recognized by the virus. Low resolution structures of CD155 complexed with poliovirus have been obtained using electron microscopy while a high resolution structures of theectodomain D1 and D2 of CD155 were solved by x-ray crystallography.

纯度:

>95% as determined by SDS-PAGE.

生物活性:

Measure by its ability to bind with recombinant human DNAM1 / CD226 in a functional ELISA assay.

Accession #:

NP_006496.2

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