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折扣/货期| 货号：GTX03213 | 规格：100μl | 目录价：￥5900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Pyruvate Dehydrogenase E1 alpha (phospho Ser293) antibody [GT1301]
别名:
pyruvate dehydrogenase E1 alpha 1 subunit , PDHA , PDHAD , PDHCE1A , PHE1A
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB
同种型:
IgG
免疫原:
A phospho specific peptide corresponding to residues surrounding S293 of human PDHA1.
克隆性:
Monoclonal
克隆号:
GT1301
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.49 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]
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