| 货号:GTX119731 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX119731-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Rad50 antibody [N1N2], N-term
别名:
RAD50 double strand break repair protein , NBSLD , RAD502 , hRad50
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC-P, IP, WB
同种型:
IgG
免疫原:
Recombinant protein encompassing a sequence within the N-terminus region of human Rad50. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.78 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
154
产品形式:
Liquid
存储溶液:
0.1M Tris, 0.1M Glycine, 20% Glycerol, 0.01% Thimerosal.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq]
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