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折扣/货期| 货号：SIH-117A | 规格：1 mg | 目录价：￥2030.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Radicicol
产品描述:
Hsp90 inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
364.8
产品形式:
White to Yellow Solid
产地:
加拿大
功能与背景:
Radicicol inhibits src (IC50=0.27µM) and src-like kinases(1), leading to hypophosphorylation of retinoblastoma tumor suppressor protein(2). It causes morphological reversion of ras-transformed cells(3) and leads to selective depletion of Raf kinase(4). It also displays anti-angiogenic activity(5), and binds to and inhibits Hsp 90 molecular chaperone(6). It binds more strongly to Hsp90 than to GRP94. It also binds to yeast HSP90, E. coli HtpG and TRAP-1. Looking for more information on HSP90? Visit our new HSP90 Scientific Resource Guide at http://www.HSP90.ca.
纯度:
97% by TLC
来源:
Produced by fermentation
CAS号:
12772-57-5
分子式:
C18H17CIO6
溶解度:
Soluble in DMSO
PubChem CID:
6323491
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