| 货号:GTX52607 | 规格:50μg | 目录价:¥8000 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
RANTES antibody [12K10]
别名:
CC motif chemokine ligand 5 , CCL5 , D17S136E , RANTES , SCYA5 , SISd , SISdelta , TCP228 , eoCP , C-C motif chemokine ligand 5
反应种属:
Human
宿主来源:
Mouse
实验应用:
Neutralizing /Inhibition, WB
同种型:
IgG1
免疫原:
Human recombinant CCL-5
克隆性:
Monoclonal
克隆号:
12K10
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
500 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
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