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折扣/货期| 货号：GTX02700 | 规格：100μg | 目录价：￥7000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Rb antibody [RB1/2313R]
别名:
RB transcriptional corepressor 1 , OSRC , PPP1R130 , RB , p105-Rb , pRb , pp110
反应种属:
Human, Mouse
宿主来源:
Rabbit
实验应用:
IHC-P
靶标/特异性:
Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein.
同种型:
IgG
免疫原:
Recombinant human full-length Rb1 protein
克隆性:
Monoclonal
克隆号:
RB1/2313R
纯化方式:
Protein A/G purified
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
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