| 货号:V7420SAF-100UG | 规格:100 ug | 目录价:¥6652.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant HLA-DQ Antibody (MHC II)
产品描述:
Recognizes a DQ antigen, which is a dimer of 60kDa. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
FACS, IF
同种型:
Rabbit IgG, kappa
免疫原:
Full length recombinant human protein was used as the immunogen for the recombinant HLA-DQ antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
HLA-DQA1/2866R
纯化方式:
Protein A affinity chromatography
保存温度:
Store the recombinant HLA-DQ antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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