| 货号:200-02RB-100UG | 规格:100 ug | 目录价:¥11191 |
| 货号:200-02RB-1MG | 规格:1 mg | 目录价:¥49507 |
| 货号:200-02RB-250UG | 规格:250 ug | 目录价:¥21623 |
| 货号:200-02RB-25UG | 规格:25 ug | 目录价:¥3004 |
| 货号:200-02RB-500UG | 规格:500 ug | 目录价:¥32117 |
| 货号:200-02RB-5UG | 规格:5 ug | 目录价:¥1207 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Recombinant Human sIL-2 Receptor Beta Fc
别名:
soluble IL-2 Receptor subunit beta, CD122 antigen, IMD63, IL15RB, P70-75
产品描述:
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis. Recombinant Human sIL-2 Receptor Beta Fc is a 53.5 kDa protein of 473 amino acids, consisting of the extracellular domain of the mature sequence, as well as a 230 C-terminal Fc region linked by two glycines. As a result of glycosylation, Recombinant Human sIL-2 Receptor Beta Fc migrates to an approximate molecular weight of 60-65 kDa, under reducing conditions.
宿主来源:
CHO cells
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Bulk
产地:
美国
生产商:
PeproTech
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