官网链接
折扣/货期| 货号：310-45-100UG | 规格：100 ug | 目录价：￥3004 |
| 货号：310-45-1MG | 规格：1 mg | 目录价：￥19458 |
| 货号：310-45-250UG | 规格：250 ug | 目录价：￥8489 |
| 货号：310-45-500UG | 规格：500 ug | 目录价：￥12618 |
| 货号：310-45-50UG | 规格：50 ug | 目录价：￥1207 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Recombinant Human Vista Fc
别名:
V-type Immunoglobulin domain containing Suppressor of T-cell Activation,Platelet receptor Gi24, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor,B7-H5, VSIR, C10orf54, SISP1, PP2135, UNQ730/PRO1412
产品描述:
VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8. Recombinant Human VISTA Fc is a 88.2 kDa homodimeric protein of 395 amino acids consisting of the extracellular domain of the mature sequence, as well as a 230-residue C-terminal Fc region linked by two glycines. As a result of glycosylation, the Recombinant Human VISTA Fc migrates to an apparent molecular weight of approximately 60-70 kDa by SDS-PAGE gel, under reducing conditions.
宿主来源:
CHO
保存温度:
Minus 20C
运输温度:
Room Temperature
产品形式:
Standard
产地:
美国
生产商:
PeproTech
您可能感兴趣的产品
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询