Recombinant Human Vista Fc-其他重组蛋白-深圳欣博盛生物科技有限公司

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Recombinant Human Vista Fc

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：310-45-100UG	规格：100 ug	目录价：￥3004
货号：310-45-1MG	规格：1 mg	目录价：￥19458
货号：310-45-250UG	规格：250 ug	目录价：￥8489
货号：310-45-500UG	规格：500 ug	目录价：￥12618
货号：310-45-50UG	规格：50 ug	目录价：￥1207

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant Human Vista Fc

别名:

V-type Immunoglobulin domain containing Suppressor of T-cell Activation,Platelet receptor Gi24, V-set domain-containing immunoregulatory receptor, V-set immunoregulatory receptor,B7-H5, VSIR, C10orf54, SISP1, PP2135, UNQ730/PRO1412

产品描述:

VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8. Recombinant Human VISTA Fc is a 88.2 kDa homodimeric protein of 395 amino acids consisting of the extracellular domain of the mature sequence, as well as a 230-residue C-terminal Fc region linked by two glycines. As a result of glycosylation, the Recombinant Human VISTA Fc migrates to an apparent molecular weight of approximately 60-70 kDa by SDS-PAGE gel, under reducing conditions.

宿主来源:

CHO

保存温度:

Minus 20C

运输温度:

Room Temperature

产品形式:

Standard

产地:

美国

生产商:

PeproTech