Recombinant NPM1 Antibody / Nucleophosmin-单抗-深圳欣博盛生物科技有限公司

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Recombinant NPM1 Antibody / Nucleophosmin

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9687-100UG	规格：100 ug	目录价：￥6414.1
货号：V9687-20UG	规格：20 ug	目录价：￥2963.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Recombinant NPM1 Antibody / Nucleophosmin

产品描述:

Recognizes a 33kDa glycoprotein identified as Nucleophosmin (NPM). It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia.

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

Rabbit IgG, kappa

免疫原:

A recombinant protein fragment was used as the immunogen for the recombinant NPM1 antibody.

克隆性:

Recombinant Rabbit Monoclonal