Recombinant Thyroglobulin Antibody / TG-单抗-深圳欣博盛生物科技有限公司

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Recombinant Thyroglobulin Antibody / TG

品牌：NSJ Bio

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说明书

折扣/货期

货号：V3630SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

Recombinant Thyroglobulin Antibody / TG

产品描述:

MAb r2H11 reacts with a partially defined epitope of human thyroglobulin. This epitope is different form the epitope recognized by MAb 6E1. Thyroglobulin is a 660kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms.

反应种属:

Human, Mouse, Rat

宿主来源:

Mouse

实验应用:

IHC-P

同种型:

Mouse IgG1, kappa

免疫原:

Human thyroid follicular cells were used as the immunogen for the recombinant Thyroglobulin antibody. The epitope recognized by mAb r2H11 is different than that recognized by mAb 6E1/r6E1.

克隆性:

Recombinant Mouse Monoclonal

克隆号:

r2H11

纯化方式:

Protein G affinity chromatography

保存温度:

Store the recombinant Thyroglobulin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

产品形式:

Purified

存储溶液:

1 mg/ml in 1X PBS; BSA free, sodium azide free