Ritonavir-抑制剂-深圳欣博盛生物科技有限公司

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Ritonavir

品牌：Adipogen

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说明书

折扣/货期

货号：AG-CR1-3683-M010	规格：10 mg	目录价：￥360
货号：AG-CR1-3683-M050	规格：50 mg	目录价：￥1320

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Ritonavir

别名:

RTV; A-84538; ABT-538; Abbot 84538; NSC 693184

产品描述:

HIV-1 and HIV-2 protease inhibitor. Glucose transporter 1 (GLUT1) and 4 (GLUT4) inhibitor. Inhibits transport of glucose across the plasma membranes of mammalian cells and consequently decreases glycolysis. Useful agent for immunometabolism research. Antitumor agent. Apoptosis inducer and cell proliferation inhibitor in GLUT1/GLUT4 overexpressed cancer cell lines. Tumor cells rely on elevated glucose consumption and metabolism for survival and proliferation. Glucose transporters mediating glucose entry are key proximal rate-limiting checkpoints. Among the fourteen SLC2A family members, GLUTs 1 and 4 are high-affinity glucose transporters. Inhibits 20S proteasome chymotrypsin-like activity. The proteinase inhibitor Kaletra, which is a mixture of the HIV-1 proteinase inhibitors lopinavir and ritonavir has been shown to be effective against SARS-CoV and MERS-CoV. Shown in a SARS-CoV-2 protease structure model study to potentially bind and inhibit the coronavirus endopeptidase C30 (CEP_C30) of SARS-CoV-2. An initial randomized trial study was not successful.

保存温度:

+4°C

运输温度:

Ambient

预期分子量:

720.9

产品形式:

solid

产地:

瑞士

纯度:

>98% (HPLC)