官网链接
折扣/货期| 货号：GTX629972 | 规格：100μl | 目录价：￥4000 |
| 货号：GTX629972-S | 规格：25μl | 目录价：￥1700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ROCK1 + ROCK2 antibody [GT464]
别名:
Rho associated coiled-coil containing protein kinase 1 , P160ROCK , ROCK-I
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG2b
免疫原:
Recombinant protein encompassing a sequence within the N-terminus region of human ROCK1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
GT464
纯化方式:
Affinity purified by Protein G.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
158
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq]
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