深圳欣博盛生物科技有限公司 a1

ROCK1 antibody
货号:GTX31836 规格:100μg 目录价:¥6200
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ROCK1 antibody
别名:
Rho associated coiled-coil containing protein kinase 1 , P160ROCK , ROCK-I
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, ICC/IF, WB
靶标/特异性:
ROCK1 antibody is predicted to not cross-react with other ROCK protein family members.
同种型:
IgG
免疫原:
ROCK1 antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human ROCK1.The immunogen is located within the first 50 amino acids of ROCK1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq, Jul 2008]
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