ROCK1 antibody-多抗-深圳欣博盛生物科技有限公司

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ROCK1 antibody

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX32843

规格：100μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

ROCK1 antibody

别名:

Rho associated coiled-coil containing protein kinase 1 , P160ROCK , ROCK-I

反应种属:

Human, Mouse

宿主来源:

Rabbit

实验应用:

IHC-P, IP, WB

同种型:

IgG

免疫原:

Recombinant fusion protein containing a sequence corresponding to amino acids 400-660 of human ROCK1 (NP_005397.1).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

158

产品形式:

Liquid

存储溶液:

PBS, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. A pseudogene, related to this gene, is also located on chromosome 18. [provided by RefSeq, Aug 2015]

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