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折扣/货期| 货号：28447-10 mg | 规格：10 mg | 目录价：￥4690 |
| 货号：28447-25 mg | 规格：25 mg | 目录价：￥10277.8 |
| 货号：28447-5 mg | 规格：5 mg | 目录价：￥2934.6 |
| 货号：28447-50 mg | 规格：50 mg | 目录价：￥13212.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SCH 546738
产品描述:
A CXCR3 antagonist (Ki = 0.4 nM); selective for CXCR3 over a panel of 49 other receptors at 10 µM; inhibits CXCL9-, CXCL10-, or CXCL11-induced chemotaxis in hemagglutinin- and IL-2-activated primary human T cells at 10 or 100 nM; increases survival in combination with cyclosporin A in a rat model of GVHD at dose of 5 mg/kg twice per day; reduces tumor growth and CD8+ T cell tumor infiltration in a murine B16/F10 melanoma model; decreases hepatic Cxcr3, TBARS, and triglyceride levels and hepatic macrophage infiltration in a mouse model of MASH induced by a methionine- and choline-deficient diet at 10 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
492.44422
产品形式:
A solid
有效期:
1460
纯度:
≥95%
CAS号:
906805-42-3
分子式:
C23H31Cl2N7O
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