SCO2 antibody-多抗-深圳欣博盛生物科技有限公司

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SCO2 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85482

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SCO2 antibody

别名:

SCO cytochrome c oxidase assembly protein 2 , CEMCOX1 , ECGF1 , Gliostatin , MYP6 , PD-ECGF , SCO1L , TP , TYMP , TdRPase

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

同种型:

IgG

免疫原:

SCO2 antibody was raised against a 19 amino acid synthetic peptide from near the carboxy terminus of human SCO2.The immunogen is located within the last 50 amino acids of SCO2.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Synthesis of cytochrome c oxidase 2 was initially identified in yeast as one of two cytochrome c oxidase (COX) assembly proteins that enable the assembly of cytochrome c holoenzyme, a complex that catalyzes the transfer of reducing equivalents from cytochrome c to molecular oxygen and pumps protons across the inner mitochondrial membrane. Like their yeast homologs, the function of both SCO2 and SCO1 are dependent on copper ion binding. Recent studies suggest that SCO2 expression is regulated by p53, so that a decrease in p53 expression, such as in numerous tumors and cells lines, the drop in SCO2 expression leads to a shift from normal aerobic respiration towards the production of glycolytic ATP. Defects in the SCO2 protein are also associated with fatal infantile cardioencephalomyopathy and COX deficiency.

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