| 货号:GTX85173 | 规格:100μg | 目录价:¥6200 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SCUBE2 antibody
别名:
signal peptide, CUB domain and EGF like domain containing 2 , CEGB1 , CEGF1 , CEGP1 , scube/You
反应种属:
Human, Rat
宿主来源:
Rabbit
实验应用:
ELISA, FCM, ICC/IF, WB
同种型:
IgG
免疫原:
SCUBE2 antibody was raised against a 17 amino acid synthetic peptide near the center of human SCUBE2.The immunogen is located within amino acids 480 - 530 of SCUBE2.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
110
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.
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