SH2D1A antibody, Internal-多抗-深圳欣博盛生物科技有限公司

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SH2D1A antibody, Internal

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX89320

规格：100μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SH2D1A antibody, Internal

别名:

SH2 domain containing 1A , DSHP , EBVS , IMD5 , LYP , MTCP1 , SAP , SAP/SH2D1A , XLP , XLPD , XLPD1

反应种属:

Human

宿主来源:

Goat

实验应用:

IP, WB

同种型:

IgG

免疫原:

Peptide with sequence C-QYPVEKKSSARSTQ, from the internal region of the protein sequence according to NP_002342.1; NP_001108409.1.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

偶联:

Unconjugated

产品浓度:

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

TBS, 0.5% BSA, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a protein that plays a major role in the bidirectional stimulation of T and B cells. This protein contains an SH2 domain and a short tail. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in this gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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