| 货号:GTX60153 | 规格:100μl | 目录价:¥5600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SHANK3 antibody
别名:
SH3 and multiple ankyrin repeat domains 3 , DEL22q13.3 , PROSAP2 , PSAP2 , SCZD15 , SPANK-2
反应种属:
Rat
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
IgG
免疫原:
KLH conjugated synthetic peptide derived from human SHANK3(1165-1215).
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
1% BSA, 50% Glycerol, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene is a member of the Shank gene family. Shank proteins are multidomain scaffold proteins of the postsynaptic density that connect neurotransmitter receptors, ion channels, and other membrane proteins to the actin cytoskeleton and G-protein-coupled signaling pathways. Shank proteins also play a role in synapse formation and dendritic spine maturation. Mutations in this gene are a cause of autism spectrum disorder (ASD), which is characterized by impairments in social interaction and communication, and restricted behavioral patterns and interests. Mutations in this gene also cause schizophrenia type 15, and are a major causative factor in the neurological symptoms of 22q13.3 deletion syndrome, which is also known as Phelan-McDermid syndrome. Additional isoforms have been described for this gene but they have not yet been experimentally verified. [provided by RefSeq, Mar 2012]
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