Shh antibody [8G3]-单抗-深圳欣博盛生物科技有限公司

首页产品中心单抗

Shh antibody [8G3]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX83231

规格：100μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Shh antibody [8G3]

别名:

sonic hedgehog signaling molecule , HHG1 , HLP3 , HPE3 , MCOPCB5 , SMMCI , ShhNC , TPT , TPTPS

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, WB

同种型:

IgG1

免疫原:

Purified recombinant fragment of human SHH expressed in E. Coli.

克隆性:

Monoclonal

克隆号:

8G3

纯化方式:

Unpurified

偶联:

Unconjugated

产品浓度:

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

Ascites, 0.03% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right

您可能感兴趣的产品

Alpha Synuclein Oligomer Antibody

货号：SMC-622S

Alpha Synuclein Oligomer Antibody: RPE

货号：SMC-622D-RPE

Alpha Synuclein Oligomer Antibody: PerCP

货号：SMC-622D-PCP

Alpha Synuclein Oligomer Antibody: HRP

货号：SMC-622D-HRP

Alpha Synuclein Oligomer Antibody: FITC

货号：SMC-622D-FITC

Alpha Synuclein Oligomer Antibody: Biotin