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折扣/货期| 货号：GTX82967 | 规格：500μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Sialosyl-Tn antigen antibody [STn 219]
别名:
CD175s antibody , Sialosyl Tn antibodys , Tn antibody
反应种属:
Human
宿主来源:
Mouse
实验应用:
ICC/IF, IHC, IHC-P
同种型:
IgG1
免疫原:
Ovine submaxillary mucin (OSM)
克隆性:
Monoclonal
克隆号:
STn 219
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
Sialyl-Tn is a carbohydrate antigen overexpressed in several epithelial cancers including breast cancer, and usually associated with poor prognosis. Sialyl-Tn is synthesized by a CMP-Neu5Ac: GalNAc alpha2,6-sialyltransferase: ST6GalNAc I, which catalyzes the transfer of a sialic acid residue in alpha2,6-linkage to the GalNAcalpha1-O-Ser/Thr structure. The resulting disaccharide (Neu5Acalpha2-6GalNAcalpha1-O-Ser/Thr) cannot be further elongated and sialyl-Tn expression results therefore in a shortening of the O-glycan chains
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