Smad1 (phospho Ser465) antibody-多抗-深圳欣博盛生物科技有限公司

首页产品中心多抗

Smad1 (phospho Ser465) antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX78944

规格：100μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Smad1 (phospho Ser465) antibody

别名:

BSP1,JV41,MADH1,MADR1,SMAD family member 1,SMAD1,Smad1

反应种属:

Human

宿主来源:

Rabbit

实验应用:

靶标/特异性:

This antibody is raised against human Smad1 phosphorylated at Ser465. Based on sequence homology, it is predicted to react with smad5 and smad8(9) when phosphorylated at the corresponding residues - smad5 Ser465 and smad8(9) Ser467.

同种型:

IgG

免疫原:

The antiserum was produced against synthesized phosphopeptide derived from human Smad1 around the phosphorylation site of serine 465 (I-S-S-V-SP).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 150mM NaCl, 0.5% BSA, 50% glycerol (Please contact us for BSA-free format), 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

您可能感兴趣的产品

Anti-Cathepsin D

货号：01-12-030104-1mg

Tafazzin Polyclonal Antibody

SARS-CoV-2 (COVID-19) nsp3 antibody

货号：GTX135589-S

SARS-CoV-2 (COVID-19) nsp12 antibody