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折扣/货期| 货号：GTX03233 | 规格：100μl | 目录价：￥5900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SMC1 (phospho Ser957) antibody [GT1321]
别名:
structural maintenance of chromosomes 1A , CDLS2 , DXS423E , SB1.8 , SMC1 , SMC1L1 , SMC1alpha , SMCB
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
IHC-P, WB
同种型:
IgG
免疫原:
A phospho specific peptide corresponding to residues surrounding S957 of human SMC1.
克隆性:
Monoclonal
克隆号:
GT1321
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
0.61 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
143
产品形式:
Liquid
存储溶液:
PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Proper cohesion of sister chromatids is a prerequisite for the correct segregation of chromosomes during cell division. The cohesin multiprotein complex is required for sister chromatid cohesion. This complex is composed partly of two structural maintenance of chromosomes (SMC) proteins, SMC3 and either SMC1B or the protein encoded by this gene. Most of the cohesin complexes dissociate from the chromosomes before mitosis, although those complexes at the kinetochore remain. Therefore, the encoded protein is thought to be an important part of functional kinetochores. In addition, this protein interacts with BRCA1 and is phosphorylated by ATM, indicating a potential role for this protein in DNA repair. This gene, which belongs to the SMC gene family, is located in an area of the X-chromosome that escapes X inactivation. Mutations in this gene result in Cornelia de Lange syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]
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