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折扣/货期| 货号：GTX22871 | 规格：200μl | 目录价：￥5000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Sodium/Potassium ATPase alpha 1 antibody [M7-PB-E9]
别名:
ATPase Na+/K+ transporting subunit alpha 1
反应种属:
Bovine, Chicken, Dog, Human, Mouse, Pig, Rat, Sheep
宿主来源:
Mouse
实验应用:
ELISA, FCM, ICC/IF, IHC, IHC-P, IP, WB
靶标/特异性:
This antibody recognizes an epitope between amino acid residues 646 and 652 of the sheep kidney alpha sodium/potassium ATPase. In rat, this antibody can only detects the alpha 3 isoform.
同种型:
IgG1
免疫原:
Purified alpha sodium/potassium ATPase from sheep kidney.
克隆性:
Monoclonal
克隆号:
M7-PB-E9
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Buffer, 0.1% BSA, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The sodium/potassium ATPase is an integral membrane enzyme found in all cells of higher organisms and is responsible for the ATP-dependent transport of sodium and potassium across the cell membrane. This membrane-bound enzyme is related to a number of other ATPases including sarcoplasmic and endoplasmic reticulum calcium ATPase (SERCA) and plasma membrane calcium ATPase (PMCA). The sodium/potassium ATPase consists of a large, multipass, transmembrane catalytic subunit, termed the alpha subunit, and an associated smaller glycoprotein, termed the beta subunit. Studies indicate that there are three isoforms of the alpha subunit (alpha 1, alpha 2, alpha 3) and two isoforms of the beta subunit (beta 1 and beta 2) encoded by two multigene families. The different isoforms of the sodium/potassium ATPase exhibit tissue-specific and developmental patterns of expression. The alpha 1 and beta mRNAs are present in all cell types examined, whereas the alpha 2 and alpha 3 mRNAs exhibit a more restricted pattern of cell-specific expression. The alpha subunit has been found in kidney, brain, heart, and to a lesser extent liver, skeletal and smooth muscle.
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