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折扣/货期| 货号：29230-1 mg | 规格：1 mg | 目录价：￥924.6 |
| 货号：29230-10 mg | 规格：10 mg | 目录价：￥5266.2 |
| 货号：29230-5 mg | 规格：5 mg | 目录价：￥3524.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GSK2982772
产品描述:
A RIPK1 inhibitor (IC50s = 16 and 2,500 nM for the human and mouse enzymes, respectively); >10,000-fold selective for RIPK1 over a panel of 339 kinases at 10 µM; inhibits necrotic cell death induced by a combination of TNF-α and the caspase inhibitor QVD-OPh in U937 human monocytic and L929 murine fibrosarcoma cells (IC50s = 6.3 and 1,300 nM, respectively); decreases IL-1β and IL-6 levels in intestinal mucosa tissue isolated from patients with ulcerative colitis at 3-300 nM; increases survival in a mouse model of TNF-α-induced lethal shock at 3, 10, and 50 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
377.39676
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1622848-92-3
分子式:
C20H19N5O3
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