官网链接
折扣/货期| 货号：V9701-100UG | 规格：100 ug | 目录价：￥6414.1 |
| 货号：V9701-20UG | 规格：20 ug | 目录价：￥2963.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SOX4 Antibody
产品描述:
SOX4 is a member of the SOX (SRY-related HMG-box) family of transcription factors with a critical role in embryonic development and in cell-fate determination during organogenesis of the heart, pancreas, brain, and in B and T lymphocyte differentiation. SOX4 gene expression is upregulated in many cancer types, and increased SOX4 activity contributes to cellular transformation, cell survival, and metastasis. Gene expression profiling has uncovered SOX4 with upregulated activity during TGF--induced epithelial-mesenchymal transition (EMT) in normal and cancerous breast epithelial cells. SOX4 is indispensable for EMT and cell survival invitro and for primary tumor growth and metastasis invivo. SOX4 is identified as a master regulator of EMT by governing the expression of the epigenetic modifier Ezh2.
反应种属:
Human
宿主来源:
Mouse
实验应用:
FACS, IF, WB, IHC-P
同种型:
Mouse IgG2b, kappa
免疫原:
A portion of amino acids 45-130 was used as the immunogen for the SOX4 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-SOX4-1D6
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the SOX4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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