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折扣/货期| 货号：V8994-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V8994-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
SP100 Antibody
产品描述:
The human SP100 gene encodes an autoantigen that co-localizes with PML and NDP52 in distinct nuclear domains, called nuclear dots (NDs) or ND10 nuclear bodies. Papova-, adeno-, and herpesviruses begin their transcription and DNA-replication at NDs, which play a role in autoimmunity, viral infections and in the etiology of acute promyelocytic leukemia. SP-100 is an interferon inducible protein that has two splice variants. One splice variant contains a highly conserved copy of the DNA-binding high mobility group 1 protein sequence, and thus represents a novel HMG-box protein. This alternatively spliced variant of SP-100 has a unique expression and localization pattern that is distinct from the SP-100 full-length protein. The SP100 protein is covalently modified by the small ubiquitin-related protein SUMO-1. SP-100 contains a functional nuclear localization signal and an ND-targeting region, which overlaps with the SP-100 homodimerization domain.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, WB, IF, IP, FACS, IHC-P
同种型:
Mouse IgG2b
免疫原:
Recombinant full-length human SP100 protein was used as the immunogen for the SP100 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-SP100-1B9
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the SP100 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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