SPRED2 antibody-多抗-深圳欣博盛生物科技有限公司

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SPRED2 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85025

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

SPRED2 antibody

别名:

sprouty related EVH1 domain containing 2 , Spred-2

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA, WB

靶标/特异性:

This Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.

同种型:

IgG

免疫原:

Spred2 antibody was raised against a 13 amino acid synthetic peptide near the center of the human Spred2.The immunogen is located within amino acids 140 - 190 of Spred2.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist. This Spred2 antibody is predicted to have no cross-reactivity to Spred1 or Spred3.

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