深圳欣博盛生物科技有限公司 a1

SSH3BP1 antibody, N-term
货号:GTX81190 规格:400μl 目录价:¥5600
产品详情
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产品名称:
SSH3BP1 antibody, N-term
别名:
abl interactor 1 , ABI-1 , ABLBP4 , E3B1 , NAP1BP , SSH3BP , SSH3BP1
反应种属:
Human
宿主来源:
Rabbit
实验应用:
FCM, IHC-P, WB
同种型:
IgG
免疫原:
KLH conjugated synthetic peptide between 81-108 amino acids from the N-terminal region of human ABI1.
克隆性:
Polyclonal
克隆号:
纯化方式:
Protein A purified, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
55
产品形式:
Liquid
存储溶液:
PBS, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10;11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14. [provided by RefSeq, Sep 2011]
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