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折扣/货期| 货号：GTX48647 | 规格：100μg | 目录价：￥5100 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
STAT5A (phospho Tyr694) antibody [5F6.F1]
别名:
signal transducer and activator of transcription 5A , AA959963 , STAT5
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ELISA, ICC/IF, IHC-P, WB
同种型:
IgG1
免疫原:
Synthetic peptide corresponding to residues surrounding Y694 of mouse STAT5a protein.
克隆性:
Monoclonal
克隆号:
5F6.F1
纯化方式:
Protein A purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
91
产品形式:
Liquid
存储溶液:
20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
生产商:
GeneTex
功能与背景:
Signal transducer and activator of transcription 5 (Stat5) belongs to a family of cytoplasmic transcription factors that can be activated (phosphorylated) by a cell surface receptor. Phosphorylation at Tyr694 is obligatory for Stat5 activation. Stat5 has two isoforms, Stat5and Stat5. Aberrant Stat5 activation has been implicated in the pathogenesis of chronic myelogenous leukemia, prostate and breast cancer and tumor metastasis. Stat5 is localized in the cytoplasm and upon phosphorylation at Y694 is translocated to the nucleus.
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