| 货号:GTX82421 | 规格:50μg | 目录价:¥7800 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
STAT6 antibody
别名:
signal transducer and activator of transcription 6 , D12S1644 , IL-4-STAT , STAT6B , STAT6C
反应种属:
Human
宿主来源:
Chicken
实验应用:
WB
同种型:
IgY
免疫原:
Immunogen Sequence: GI # 23397678, sequence 61-275 Recombinant signal transducer and activator of transcription 6
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by affinity chromatography
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
94
产品形式:
Liquid
存储溶液:
PBS, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Carries out a dual function: signal transduction and activation of transcription. Involved in interleukin-4 signalling. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors. STAT family members are phosphorylated by the receptor associated kinases. and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L). which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells. expression of cell surface markers. and class switch of immunoglobulins.
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