| 货号:GTX80312 | 规格:50μl | 目录价:¥7600 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SUN2 antibody
别名:
Sad1 and UNC84 domain containing 2 , UNC84B
反应种属:
Mouse
宿主来源:
Rabbit
实验应用:
ICC/IF, WB
靶标/特异性:
Mouse SUN2
同种型:
IgG
免疫原:
Mouse SUN2 residues 1-18
克隆性:
Polyclonal
克隆号:
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Serum, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]
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