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折扣/货期| 货号：83-230 | 规格：100 uL | 目录价：￥9477 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Acetyl-alpha Tubulin -K40 Rabbit Recombinant Antibody
别名:
LIS3; TUBA3; B-ALPHA-1
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
WB, IF/ICC, ELISA
同种型:
IgG
克隆性:
Monoclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
Batch dependent
保存温度:
Store at -20℃. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
预期分子量:
55kDa
产品形式:
Liquid
存储溶液:
Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
产地:
美国
生产商:
Prosci
功能与背景:
Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blot studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, intellectual disability, and early-onset epilepsy caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Accession #:
Q71U36
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