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折扣/货期| 货号：GTX01833 | 规格：500μl | 目录价：￥5900 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TCL1A antibody [ZM92]
别名:
T cell leukemia/lymphoma 1A , TCL1
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
IgG1
免疫原:
Recombinant human TCL1 protein fragment (around aa 2-109)
克隆性:
Monoclonal
克隆号:
ZM92
纯化方式:
Purified IgG
偶联:
Unconjugated
产品浓度:
Batch dependent (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
Tris-HCl, 0.2% BSA, 0.09% Sodium azide.
生产商:
GeneTex
功能与背景:
Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010]
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