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折扣/货期| 货号：GTX29317 | 规格：50μg | 目录价：￥3700 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TCR alpha + TCR beta antibody [R73] (FITC)
别名:
RATTCBC1 , MGC109620 , TCR alpha + beta , TCB , RATTCB , Tcrb , TCBC1 , 24820
反应种属:
Rat
宿主来源:
Mouse
实验应用:
FCM, IHC-Fr
靶标/特异性:
Detects a T cell-specific heterodimeric 40 and 46 kD cell surface protein that is expressed on the vast majority, but not all, peripheral rat T cells. Induces blastoid transformation and IL2R expression in T-cells when cross linked on an artificial surface. It also induces cell proliferation when exogenous IL-2 is added.
同种型:
IgG1
免疫原:
Rat T Blasts
克隆性:
Monoclonal
克隆号:
R73
纯化方式:
Protein G purified
偶联:
FITC
产品浓度:
0.1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. Protect from light.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
The receptors on T cells consist of immunoglobulin like integral membrane glycoproteins containing 2 polypeptide subunits, alpha and beta, of similar molecular weight, 40 to 55 kD in the human. Like the immunoglobulins of the B cells, each T cell receptor subunit has, external to the cell membrane, an N terminal variable domain and a C terminal constant domain. T cell receptors recognise foreign antigens which have been processed as small peptides and bound to major histocompatibility complex molecules at the surface of antigen presenting cells. Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci.
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