TCR gamma + delta antibody [5A6.E91] (FITC)-单抗-深圳欣博盛生物科技有限公司

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TCR gamma + delta antibody [5A6.E91] (FITC)

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品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX15596

规格：100test

目录价：￥5000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TCR gamma + delta antibody [5A6.E91] (FITC)

别名:

T cell receptor delta locus , T cell receptor gamma locus , TCRD , TCRDV1 , TRD@ , TCRG , TRG@

反应种属:

Human, Primate

宿主来源:

Mouse

实验应用:

ELISA, FCM, ICC/IF, IHC, Neutralizing/Inhibition

同种型:

IgG1

免疫原:

Pan TCR gamma delta

克隆性:

Monoclonal

克隆号:

5A6.E91

纯化方式:

Protein A purified

偶联:

FITC

产品浓度:

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. Protect from light.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.5% BSA, Glycerol, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor gamma locus. The gamma locus includes V (variable), J (joining), and C (constant) segments. During T cell development, the gamma chain is synthesized by a recombination event at the DNA level joining a V segment with a J segment; the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random addition of nucleotides by terminal deoxynucleotidyltransferase. Several V segments of the gamma locus are known to be incapable of encoding a protein and are considered pseudogenes. Somatic rearrangement of the gamma locus has been observed in T cells derived from patients with T cell leukemia and ataxia telangiectasia. [provided by RefSeq]

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