TCR V delta 1 antibody [TS8.2]-单抗-深圳欣博盛生物科技有限公司

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TCR V delta 1 antibody [TS8.2]

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX79232

规格：200μg

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TCR V delta 1 antibody [TS8.2]

别名:

T cell receptor delta variable 1 , hDV101S1

反应种属:

Human, Primate

宿主来源:

Mouse

实验应用:

Activation, ELISA, FCM, ICC/IF, IHC, IHC-Fr, Neutralizing/Inhibition

同种型:

IgG1

免疫原:

Human TCR V delta 1

克隆性:

Monoclonal

克隆号:

TS8.2

纯化方式:

Protein G purified

偶联:

Unconjugated

产品浓度:

0.15 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.5% BSA, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

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