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折扣/货期| 货号：GTX85175 | 规格：25μl | 目录价：￥6200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TCTN3 antibody
别名:
amyloid beta precursor protein , AAA , ABETA , ABPP , AD1 , APPI , CTFgamma , CVAP , PN-II , PN2 , preA4
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
Dot, ELISA, IHC-P, Sandwich ELISA
靶标/特异性:
This antibody specifically recognizes beta amyloid aggregates but not peptide monomers.
同种型:
IgG2b
免疫原:
The immunogen used to generate this antibody corresponds to Beta amyloid (1-42).
克隆性:
Monoclonal
克隆号:
GT622
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
0.27 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014]
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