TEM1 antibody-多抗-深圳欣博盛生物科技有限公司

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TEM1 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX85429

规格：100μg

目录价：￥6200

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

TEM1 antibody

别名:

CD248 molecule , CD164L1 , TEM1

反应种属:

Human

宿主来源:

Rabbit

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

At least two isoforms of TEM1 are known to exist; this antibody recognizes only the larger isoform.

同种型:

IgG

免疫原:

TEM1 antibody was raised against a 14 amino acid synthetic peptide near the amino terminus of the human TEM1.The immunogen is located within amino acids 40 - 90 of TEM1.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion. At least two isoforms of TEM1 are known to exist; this antibody recognizes only the larger isoform.

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