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折扣/货期| 货号：GTX627420 | 规格：100μl | 目录价：￥4000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
TET1 antibody [GT1462]
别名:
tet methylcytosine dioxygenase 1 , CXXC6 , LCX , bA119F7.1
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
ICC/IF, IHC-P, WB
同种型:
IgG2b
免疫原:
Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
GT1462
纯化方式:
Affinity purified by Protein G.
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 20% Glycerol, no preservatives.
生产商:
GeneTex
功能与背景:
Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
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